Innovative Doppler US methods
Significant contributions of the lab in this field include:
Development of a novel approach for blood flow measurements based on the Doppler peak frequency
Development of an original signal processing approach (Multigate Spectral Doppler Analysis - MSDA) for real-time display of blood velocity profiles in human vessels
P.Tortoli, G.Guidi, P.Berti, F.Guidi, D.Righi, An FFT-based flow profiler for high-resolution in vivo investigations, Ultrasound in Medicine & Biology, 23:6, 899-910, 1997.
S.Ricci, M. Cinthio, A. Ahlgren, P.Tortoli. Accuracy and Reproducibility of a Novel Dynamic Volume Flow Measurement Method, Ultrasound in Medicine and Biology. 39:10, October 2013, Pages 1903-1914 http://dx.doi.org/10.1016/j.ultrasmedbio.2013.04.017)
Better comprehension of hemodynamics in carotid arteries, aorta, maternal/fetal vessels based on MSDA
D. Vilkomerson, S. Ricci, P. Tortoli. Finding the Peak Velocity in a Flow from its Doppler Spectrum. IEEE Trans. Ultrason., Ferroelect., Freq. Contr., 60:10, pp.2079-2088, 2013. (DOI http://dx.doi.org/10.1109/TUFFC.2013.2798)
P.Tortoli, G.Bambi, F. Guidi, R. Muchada, Towards a better quantitative measurement of aortic flow, Ultrasound in Medicine and Biology, 28:2, 249-257, 2002
P.Tortoli, V. Michelassi, G. Bambi, F. Guidi, D. Righi, Interaction between secondary velocities, flow pulsation and vessel morphology in the common carotid artery, Ultrasound in Medicine and Biology, 29:3, 407-415, 2003
G. Urban, P. Vergani, A. Ghidini, P. Tortoli, S. Ricci, P. Patrizio and M.J. Paidas, State of the art: Non-invasive ultrasound assessment of the uteroplacental circulation, Seminars in Perinatology, Vol.31, 232-239 , 2007.
Simultaneous detection of wall shear rate and distension in human arteries
P.Tortoli, T. Morganti, G. Bambi, C. Palombo, K.V. Ramnarine, Noninvasive Simultaneous Assessment of Wall Shear Rate and Wall Distension in Carotid Arteries, Ultrasound in Med. & Biol., 32:11, 1661-1670, 2006.
P. Tortoli, C. Palombo, L. Ghiadoni, G. Bini, And L. Francalanci. Simultaneous Ultrasound Assessment of Brachial Artery Shear Stimulus and Flow-Mediated Dilation during Reactive Hyperemia, Ultrasound in Med. & Biol., Vol. 37, No. 10, pp. 1561-1570, 2011 (doi:10.1016/j.ultrasmedbio.2011.06.001)
Development of an original method for analysis of PW Doppler signals beyond the Nyquist limit
P.Tortoli, A Tracking FFT Processor for Pulsed Doppler Analysis Beyond the Nyquist Limit, IEEE Transactions on Biomedical Engineering, 36:2, 232 237, 1989
Clinical application of the Transverse Doppler technique, where the ultrasound beam is at 90° to the vessel under investigation
P.Tortoli, G.Guidi, P.Pignoli, Transverse Doppler Spectral Analysis for a Correct Interpretation of Flow Sonograms, Ultrasound in Medicine and Biology, 19:2, 115-121, 1993.
Development of original Vector Doppler methods
P. Tortoli, G. Bambi, S. Ricci, Accurate Doppler Angle Estimation for Vector Flow Measurements, IEEE Trans. Ultrason., Ferroelect.,Freq. Contr. , 53:8, 1425-1531, 2006.
P. Tortoli, A. Dallai, E. Boni, L. Francalanci, S. Ricci, An Automatic Angle Tracking Procedure for Feasible Vector Doppler Blood Velocity Measurements, Ultrasound in Medicine and Biology, Vol. 36, No. 3, pp. 488-496, 2010. doi:10.1016/j.ultrasmedbio.2009.11.004.
S.Ricci, L.Bassi, P.Tortoli (2014). Real Time Vector Velocity Assessment through Multigate Doppler and Plane Waves. IEEE Trans. Ultrason., Ferroelect., Freq. Contr. vol. 61, no. 2, February 2014, pp.314-324. (DOI http://dx.doi.org/10.1109/TUFFC.2014.2911)
M.Lenge, A.Ramalli, E.Boni, H.Liebgott, C. Cachard, P.Tortoli (2014). High-frame-rate 2-D vector blood flow imaging in the frequency domain, IEEE Trans. Ultrason., Ferroelect., Freq. Contr, Vol. 61, N. 9, pp. 1504-1514. (DOI: http://dx.doi.org/10.1109/TUFFC.2014.3064)
Contribution to the development of an original method for noninvasive hematocrit measurements
W. Secomski, A. Nowicki, F. Guidi, P. Tortoli and P.A. Lewin, Non-invasive, In-vivo Measurements of Hematocrit, J Ultrasound Med, 22:375-384, 2003.
Hardware implementation of Continuous Wave and Single-Gate Pulsed Wave (PW) systems for investigation of blood flow in human arteries.
These activities led to the production of a commercial system by a national company